22 research outputs found

    Effect of deformation on components of internal stress tensor in grains of FCC-polycristal

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    Study of contributions of internal stress tensor components in deformed of austenitic steel was carriedout. The tensor components of internal stresses were determined with using bending extinction contours observing on electron microscope images of the steel

    MULTIVARIATE ANALYSES TO DETERMINE THE ORIGIN OF SOME POLYCYCLIC AROMATIC HYDROCARBONS (PAHs) IN HONEY SAMPLES

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    WOS: 000381320400029This study tries to reveal the levels of three distinct PAHs (naphthalene, benzo[a]pyrene (BaP) and anthracene on honey samples. They were taken from several different stations from the Nigde City (Central Anatolia, Turkey). The Gas chromatography-mass spectrometry results revealed that twenty-four honey samples having naphthalene residues (for GC-MS limit of detection is 1 ppb and the upper limit 100 ppb in the European Union MRLs). In addition six samples have BaP residues (1.51 +/- 0.47 ng/g) and eight examples have anthracene residues (1.59 +/- 0.85 ng/g). Heavy metals in the honey samples were studied on Pb, Ni, Cr and Cd elements. To get simple and multivariate statistics, the SPSS Statistics 21 software has been used for this work. According to simple statistics, maximum minimum values for Pb are 4286-1998; Ni 9987-5457; Cr 9654-2335 and Cd 3229-1090. However, we get higher statistics values from Cr and Cd. These results could decrease the quality of honey.Scientific Research Projects Unit of Akdeniz UniversityThe financial support of the Scientific Research Projects Unit of Akdeniz University is gratefully acknowledged

    Mutational analysis and genotype/phenotype correlation in Turkish Charcot-Marie-Tooth Type I and HNPP patients

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    The major Charcot-Marie-Tooth Type 1 (CMT1) locus, CMT1A, and Hereditary neuropathy with liability to pressure palsies (HNPP) cosegregate with a 1.5-Mb duplication and a 1.5-Mb deletion, respectively, in band 17p11.2. Point mutations in peripheral myelin gene 22 (PMP22), myelin protein zero (MPZ), and connexin 32 (Cx32) have been reported in CMT1, and in PMP22 in HNPP patients without deletion. We have screened 54 CMT1 patients, of variable clinical severity, and 25 HNPP patients from Turkey, with no duplication or deletion, for mutations in the PMP22 and Cx32 genes. A novel frameshift mutation affecting the second extracellular domain of PMP22 was found in an HNPP patient, while a point mutation in the second transmembrane domain of the protein was detected in a CMT1 patient. Two point mutations affecting different domains of Cx32 were identified in two CMTX patients. Another patient was found to carry a polymorphism in a non-conserved codon of the Cx32 gene. The clinical phenotypes of the patients correlate well with the effect of the mutation on the protein
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